Cargando...
Fecha
2021-08-06
Derechos de acceso
info:eu-repo/semantics/openAccess
Título de la revista
ISSN de la revista
Título del volumen
Editorial
Taylor & Francis
Citas
Resumen
Primary objective
The aim of the study was twofold. First, to study the relationship among apathy in the long term, initial clinical measures, and standard outcome scores after traumatic brain injury (TBI). Second, to describe white matter integrity correlates of apathy symptoms.
Research Design
Correlational study. Methods and Procedures: Correlation and Bayesian networks analyses were performed in a sample of 40 patients with moderate to severe TBI in order to identify the relationship among clinical variables, functionality, and apathy. A diffusion tensor imaging study was developed in 25 participants to describe correlations between fractional anisotropy (FA) measures and apathetic symptoms.
Main outcomes and results
Correlation analysis revealed associations between pairs of variables as apathy in the long term and functional score at discharge from hospital. Bayesian network illustrated the relevant role of axonal injury mediating the relationship between apathy and initial clinical variables. FA in the superior longitudinal fasciculus, the inferior longitudinal fasciculus, and the internal capsule were negatively correlated with apathy measures. Widespread brain areas showed positive correlations between FA and apathy.
Conclusions
These results highlight the relevance of white matter integrity measures in initial assessment after TBI and its relationship with apathetic manifestations in the chronic phase.
Descripción
This is an Accepted Manuscript of an article published by Taylor and Francis Group in "Brain Injury, 35(9), 1043–1053", available at: https://doi.org/10.1080/02699052.2021.1953145
Este es el manuscrito aceptado del artículo publicado por Taylor and Francis Group en "Brain Injury, 35(9), 1043–1053", disponible en línea: https://doi.org/10.1080/02699052.2021.1953145
Este es el manuscrito aceptado del artículo publicado por Taylor and Francis Group en "Brain Injury, 35(9), 1043–1053", disponible en línea: https://doi.org/10.1080/02699052.2021.1953145
Categorías UNESCO
Palabras clave
traumatic brain injury, white matter, DT, Bayesian networks, apathy
Citación
Navarro-Main, B., Castaño-León, A., Hilario, A., Lagares, A., Rubio, G., Periañez, J., … INERTIA group collaborators. (2021). Apathetic symptoms and white matter integrity after traumatic brain injury. Brain Injury, 35(9), 1043–1053. https://doi.org/10.1080/02699052.2021.1953145
Centro
Facultad de Psicología
Departamento
Psicología Básica II
Grupo de investigación
Estudios de Criminología y Política Criminal (GECYP)
Grupo de Investigación en Neurociencia cognitiva y Neuroimagen (GINN)
Grupo de Investigación en Neurociencia cognitiva y Neuroimagen (GINN)