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A holistic review of fentanyl use and its impact on public health

dc.contributor.authorBorrego Ruiz, Alejandro
dc.date.accessioned2025-07-01T10:54:05Z
dc.date.available2025-07-01T10:54:05Z
dc.date.issued2024-12-31
dc.descriptionThe registered version of this article, first published in “Current Addiction Research, 8, 2024", is available online at the publisher's website: Üsküdar University, https://doi.org/10.32739/car.2024.8.2.229 La versión registrada de este artículo, publicado por primera vez en “Current Addiction Research, 8, 2024", está disponible en línea en el sitio web del editor: Üsküdar University, https://doi.org/10.32739/car.2024.8.2.229
dc.description.abstractFentanyl is a synthetic opioid that was engineered to provide a potent analgesic effect, with its medical utility widely established in clinical contexts such as pain management and anesthesia. Fentanyl use has become a critical public health issue due to diversion for misuse and to rapidly proliferation of illicit manufacturing. This persistent increase in illicitly manufactured fentanyl distribution shows no indication of decline, raising significant concerns regarding its impact on public health and opioid misuse trends, including a dramatic increase in overdose deaths. Moreover, individuals from socially or economically precarious backgrounds, as well as those suffering from mental health disorders, are particularly vulnerable, as limited access to resources and support systems can lead to increased substance use as a coping mechanism for stress and adversity. Therefore, the objective of this narrative review is to provide a holistic overview on fentanyl, addressing its synthesis process, pharmacology and clinical use, relationship with gut microbiome, epidemiology and global distribution, patterns of use and motivations, and overdose treatment. For this purpose, current and relevant evidence on fentanyl and its correlates has been conscientiously assessed and outlined.en
dc.description.provenanceMade available in DSpace on 2025-07-01T10:54:05Z (GMT). No. of bitstreams: 1 Borrego_Ruiz_Alejandro_Fentanyl_Use_ALEJANDRO BORREGO RU.pdf: 289912 bytes, checksum: fa0a480049ce772cb0b376d91179a1b6 (MD5) Previous issue date: 2024-12-31en
dc.description.versionversión publicada
dc.identifier.citationBorrego-Ruiz, A. (2024). A holistic review of fentanyl use and its impact on public health. Current Addiction Research, 8(2), 23-33. https://doi.org/10.32739/car.2024.8.2.229
dc.identifier.doihttps://doi.org/10.32739/car.2024.8.2.229
dc.identifier.issn2548-0715
dc.identifier.urihttps://hdl.handle.net/20.500.14468/26958
dc.journal.issue2
dc.journal.titleCurrent Addiction Research
dc.journal.volume8
dc.language.isoen
dc.page.final33
dc.page.initial23
dc.publisherÜsküdar University
dc.relation.centerFacultad de Psicología
dc.relation.departmentPsicología Social y de las Organizaciones
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject61 Psicología
dc.subject.keywordsfentanyl useen
dc.subject.keywordsgut microbiomeen
dc.subject.keywordsepidemiologyen
dc.subject.keywordsmotivationsen
dc.subject.keywordsoverdose treatmenten
dc.titleA holistic review of fentanyl use and its impact on public healthen
dc.typejournal articleen
dspace.entity.typePublication
relation.isAuthorOfPublication4056d333-e1b2-4759-8b5a-af6f4e202fd8
relation.isAuthorOfPublication.latestForDiscovery4056d333-e1b2-4759-8b5a-af6f4e202fd8
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