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Fecha
2020-11-25
Derechos de acceso
info:eu-repo/semantics/openAccess
Título de la revista
ISSN de la revista
Título del volumen
Editorial
Oxford University Press; European Society of Cardiology
Citas
Resumen
Abstract
Introduction
Pulmonary hypertension (PH) is defined as mean pulmonary arterial pressure (mPAP) ≥25 mmHg at rest, measured by right heart catheterization (RHC).
Purpose
To describe classical and myocardial deformation echocardiographic parameters in patients with established PH and to identify prognostic variables
Methods
We prospectively enrolled 76 patients with mPAP ≥25 mmHg undergoing RHC between 2017 and 2018. All subjects underwent transthoracic echocardiography (TTE) according to the latest ASE/EACVI guidelines the same day of the RHC. Strain analysis was carried out by speckle-tracking echocardiography (QLAB 10.7, Philips). Clinical events during the follow-up were: acute heart failure hospitalization, cardiac transplant and all-cause mortality.
Results
Mean age was 59±12, 43.4% were women and 49 patients (64.5%) belonged to group 2 of PH. The median follow-up was 288 (ICR 92–534) days. Total number of events was 42 (55.3%, 9 deaths). Variables associated to events are shown in Table 1. All classic LV and RV systolic function and strain parameters were associated with a worse prognosis, being free-wall RV longitudinal strain (RVLS) the only one that remained as a prognostic factor in mutivariate analysis. Other variables associated with a worse prognosis were PCP>15 mmHg and NT-proBNP>1800, the latter being independent predictor of events. The attached figure shows event-free survival curves for the global population divided according to whether or not they belong to group II PH.
Conclusions
Our data highlight the prognostic value of free-wall RVLS and NT-proBNP in patients with established PH. NT-ProBNP was only useful in group II PH while free-wall RVLS identified patients with a higher risk of events in both groups, mainly in patients with heart disease
Descripción
The registered version of this article, first published in European Heart Journal, is available online at the publisher's website: Oxford University Press; European Society of Cardiology, https://doi.org/10.1093/ehjci/ehaa946.0141
La versión registrada de este artículo, publicado por primera vez en European Heart Journal, está disponible en línea en el sitio web del editor: Oxford University Press; European Society of Cardiology, https://doi.org/10.1093/ehjci/ehaa946.0141
La versión registrada de este artículo, publicado por primera vez en European Heart Journal, está disponible en línea en el sitio web del editor: Oxford University Press; European Society of Cardiology, https://doi.org/10.1093/ehjci/ehaa946.0141
Categorías UNESCO
Palabras clave
Tissue Doppler, Speckle Tracking, Strain Imaging
Citación
Monivas Palomero, V., Remior, P., García-Rodríguez, D., García-Gómez, S., García-Izquierdo, E., Borrego, A., Navarro, S., Martínez Mingo, A., Arellano-Serrano, C., Oteo, J. F., García-Touchard, A., Goicolea, J. F., Hernández Pérez, F., & Mingo, S. (2020). Usefulness of strain imaging to determine prognosis in pulmonary hypertension. European Heart Journal, 41(Suppl 2), ehaa946.0141. https://doi.org/10.1093/ehjci/ehaa946.0141
Centro
Facultad de Psicología
Departamento
Metodología de las Ciencias del Comportamiento