Persona: Morillo Cuadrado, Daniel Vicente
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Morillo Cuadrado
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Daniel Vicente
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Publicación Worldwide mapping of initiatives that integrate population cohorts(Frontiers Media, 2022-10-03) Rico Uribe, Laura Alejandra; Morillo Cuadrado, Daniel Vicente; Rodríguez Laso, Ángel; Vorstenbosch, Ellen; Weser, Andreas J.; Fincias, Laura; Marcon, Yannick; Rodriguez Mañas, Leocadio; Haro, Josep María; Ayuso-Mateos, Jose Luis; Morillo Cuadrado, Daniel VicentePublicación Changes in depression and suicidal ideation under severe lockdown restrictions during the first wave of the COVID-19 pandemic in Spain: A longitudinal study in the general population(Cambridge University Press, 2021-06-21) Ayuso-Mateos, Jose Luis; Morillo Cuadrado, Daniel Vicente; Haro, J. M.; Olaya, B.; Lara, Elvira; Miret, M.; Morillo Cuadrado, Daniel VicenteAims To assess whether there is a change in the prevalence of depression and suicidal ideation after the strict lockdown measures due to the first wave of the COVID-19 pandemic in Spain; and to assess which are the factors associated with the incidence of a depressive episode or suicidal ideation during the lockdown. Methods Data from a longitudinal adult population-based cohort from the provinces of Madrid and Barcelona were analysed (n = 1103). Structured face-to-face home-based interviews (pre-pandemic) and telephone interviews were performed. Both depression and suicidal ideation were assessed through an adaptation of the Composite International Diagnostic Interview (CIDI 3.0). A variety of validated instruments and sociodemographic variables including age, sex, educational level, occupational status, home quietness, screen time, resilience, loneliness, social support, physical activity, disability, economic situation and COVID-19-related information were also considered. Population prevalence estimates and multivariable logistic regressions were computed. Results Overall, prevalence rates of depression and suicidal ideation did not change significantly from before to after the COVID-19 outbreak. However, the rates of depression among individuals aged 50+ years showed a significant decrease compared to before the pandemic (from 8.48 to 6.41%; p = 0.01). Younger individuals (odds ratio (OR) = 0.97 per year older; 95% confidence interval (CI) = 0.95–0.99) and those feeling loneliness (OR = 1.96; 95% CI = 1.42–2.70) during the lockdown were at an increased risk of developing depression during the confinement. Resilience showed a protective effect against the risk of depression (OR = 0.46; 95% CI = 0.32–0.66) and suicidal ideation (OR = 0.33; 95% CI = 0.16–0.68), whereas individuals perceiving social support were at a lower risk of developing suicidal thoughts (OR = 0.35; 95% CI = 0.18–0.69). Conclusions Continuous reinforcement of mental health preventive and intervening measures during and in the aftermath of the crisis is of global importance, particularly among vulnerable groups who are experiencing the most distress. Future research should strive to evaluate the long-term effects of the COVID-19 crisis on mental health.Publicación Cohort Profile: The Spanish Longitudinal Study on Ageing and Health (Edad Con Salud)(Oxford University Press, 2022-06-17) Lara, Elvira; Miret, Marta; Olaya, Beatriz; Caballero, Francisco Félix; Morillo Cuadrado, Daniel Vicente; Moneta, María Victoria; Haro, Josep Maria; Ayuso-Mateos, Jose Luis; Morillo Cuadrado, Daniel VicentePublicación The ontogeny of an article: Using GitHub and R to stimulate Open Science(2023-04-14) Francia, Lea; Rodríguez Prada, C.; Mediavilla Torres, R.; Morillo Cuadrado, Daniel Vicente; Morillo Cuadrado, Daniel VicentePublicación Hematic Antegrade Repriming Reduces Emboli on Cardiopulmonary Bypass: A Randomized Controlled Trial(Lippincott, Williams & Wilkins, 2023-03) Blanco Morillo, Juan; Salmerón Martínez, Diego; Morillo Cuadrado, Daniel Vicente; Arribas Leal, Jose María; Puis, Luc; Verdú Verdú, Alicia; Martínez Molina, Mercedes; Tormos Ruiz, Encarnación; Sornichero Caballero, Angel; Ramírez Romero, Pablo; Farina, Piero; Cánovas López, Sergio; Morillo Cuadrado, Daniel VicenteParticulate and gaseous microemboli (GME) are side effects of cardiac surgery that interfere with postoperative recovery by causing endothelial dysfunction and vascular blockages. GME sources during surgery are multiple, and cardiopulmonary bypass (CPB) is contributory to this embolic load. Hematic antegrade repriming (HAR) is a novel procedure that combines the benefits of repriming techniques with additional measures, by following a standardized procedure to provide a reproducible hemodilution of 300 ml. To clarify the safety of HAR in terms of embolic load delivery, a prospective and controlled study was conducted, by applying Doppler probes to the extracorporeal circuit, to determine the number and volume of GME released during CPB. A sample of 115 patients (n = 115) was considered for assessment. Both groups were managed under strict normothermia, and similar clinical conditions and protocols, receiving the same open and minimized circuit. Significant differences in GME volume delivery (control group [CG] = 0.28 ml vs. HAR = 0.08 ml; p = 0.004) and high embolic volume exposure (>1 ml) were found between the groups (CG = 30.36% vs. HAR = 4.26%; p = 0.001). The application of HAR did not represent an additional embolic risk and provided a four-fold reduction in the embolic volume delivered to the patient (coefficient, 0.24; 95% CI, 0.08–0.72; p = 0.01), which appears to enhance GME clearance of the oxygenator before CPB initiation.Publicación Effect of External Irrelevant Distracters on a Visual Search Test in School-Age Children: Computerized Assessment(Sage Journals, 2021-08-13) Quiroga, M. Ángeles; Santacreu, J.; López-Cavada, C.; Capote, E.; Morillo Cuadrado, Daniel Vicente; Morillo Cuadrado, Daniel VicenteObjective: This study aimed to test the effect of an irrelevant external distracter included in a computer-administered visual search test. Two hypotheses were tested: (a) If the distracter affects performance, attention efficiency will be lowered; (b) if children do not habituate to the distracter, performance will be lower for every item of the test. Method: Distraction was induced changing the screen color unexpectedly several times in each trial—450 children (225 girls and 225 boys) from second to sixth course were tested. This group was compared with a group of 423 children from the same age range who were tested with the same test without distraction. Results: Induced distraction reduced attention efficiency for all ages and for every trial in the treatment group (test with distraction). Speed was lower, but number of errors did not increase. Conclusion: School-age children cope with an irrelevant external distracter by reducing speed, not accuracy.Publicación Changes in depression and suicidal ideation under severe lockdown restrictions during the first wave of the COVID-19 pandemic in Spain: A longitudinal study in the general population - RETRACTION(Cambridge University Press, 2023-03-13) Ayuso-Mateos, Jose Luis; Morillo Cuadrado, Daniel Vicente; Haro, J. M.; Olaya ,B.; Lara, Elvira; Miret, M.; Morillo Cuadrado, Daniel VicenteThe authors would like to retract the entire article above based on a genuine error noticed after publication. More precisely, as part of further analysis with the data set, they discovered the depression variables were inadvertently mislabeled (e.g., lifetime depression was labeled as 12-months depression). Consequently, the results and conclusions of the article are significantly affected. On the one hand, the prevalence of depression increased significantly. On the other hand, the analyses that explored the factors associated with the incidence of depression and suicidal ideation have also been affected. In the final regression model for depression, the coefficient for COVID-19 concern was found to be significant, along with the post-measures of loneliness and resilience. In addition, the final regression model for suicidal ideation showed significant associations for the Post-measures variables of social support and disability. The authors apologize for the inconveniences that this incident may have caused to the readers. A new corrected version of the research will be resubmitted and resupplied later.Publicación Changes on depression and suicidal ideation under severe lockdown restrictions during the first wave of the COVID-19 pandemic in Spain: A longitudinal study in the general population(Cambridge University Press, 2023-09-01) Ayuso-Mateos, Jose Luis; Morillo Cuadrado, Daniel Vicente; Haro, J. M.; Olaya, B; Lara, Elvira; Miret, M; Morillo Cuadrado, Daniel VicenteAims. To assess whether there is a change in the prevalence of depression and suicidal ideation after the strict lockdown measures due to the first wave of the COVID-19 pandemic in Spain, and to assess which are the factors associated with the incidence of a depressive episode or suicidal ideation during the lockdown. Methods. Data from a longitudinal adult population-based cohort from Madrid and Barcelona were analysed (n = 1103). Face-to-face home-based (pre-pandemic) and telephone interviews were performed. Depression and suicidal ideation were assessed through an adaptation of the Composite International Diagnostic Interview (CIDI 3.0). Population prevalence estimates and Multivariable logistic regressions were computed. Results. Prevalence rates of depression changed significantly from before to after the COVID-19 outbreak (from 3.06% to 12.00%; p = 0.01) and per sex and age groups. Individuals reporting COVID-19 concerns (odds ratio [OR] = 3.11; 95% confidence interval [CI] = 1.45–6.69) and those feeling loneliness (OR = 1.99; 95% CI = 1.52–2.61) during the lockdown were at increased risk of developing depression during the confinement. Resilience showed a protective effect against the risk of depression (OR = 0.57; 95% CI = 0.39–0.83), while individuals perceiving social support during the confinement were at lower risk of developing suicidal thoughts (OR = 0.21; 95% CI = 0.09–0.46). Greater disability during the lockdown was also associated with the risk of suicidal ideation (OR = 2.77; 95% CI = 1.53–5.03). Conclusions. Continuous reinforcement of mental health preventive and intervening measures is of global importance, particularly among vulnerable groups who are experiencing the most distress. Future research should strive to evaluate the long-term effects of the COVID-19 crisis on mental health.Publicación Diagnostic accuracy of the Spanish version of the 4AT scale (4AT-ES) for delirium screening in older inpatients(Elsevier, 2022-07) Delgado Parada, E.; Morillo Cuadrado, Daniel Vicente; Saiz Ruiz, J; Cebollada Gracia, A.; Ayuso-Mateos, Jose Luis; Cruz Jentoft, A.J.; Morillo Cuadrado, Daniel VicenteAbstract Background and objectives The 4AT scale is a sensitive tool for screening delirium, which can be applied rapidly in clinical settings without any specific training. It has not been translated, adapted, and validated to assess Spanish older adults. The aims of the study are: to translate and adapt to Spanish culture the 4AT scale, to present evidence of the diagnostic accuracy of this version (4AT-ES) when applied in non-specialized hospital wards, and to assess the loss of diagnostic accuracy in presence of risk factors. Methods A prospective sample was independently assessed on the 4AT-ES and the reference standard. One hundred and twenty-one inpatients (70+ years) for whom a psychiatric assessment was requested were included. Out of them, 50 were diagnosed with delirium. Nurses without specific training applied the 4AT-ES, and experienced psychiatrists cast the reference standard diagnosis (DSM-V criteria). Results Patients with delirium were older and had more risk factors (more previous delirium episodes, a higher likelihood of prior dementia/cognitive impairment) than controls. The 4AT-ES had excellent validity, sensitivity (96%) , and specificity (83.1%). The area under the curve was 0.918; in the subsample with any of those risk factors, its value did not decrease. Conclusion The 4AT-ES version of the 4AT scale was developed. When applied by non-specifically trained, nursing staff it showed excellent validity, sensitivity, and specificity, even in a subsample with previous risk factors. All indices were comparable to the original version. We recommend its use for efficient delirium screening in hospitalized older patients with suspected delirium.Publicación Herramientas para trabajar colaborativamente: El uso de GitHub y R en la creación de variables resultado en el proyecto ‘Edad con Salud’(2023-10-06) Rodríguez-Prado, Cristina; Francia, Lea; Morillo Cuadrado, Daniel Vicente