Persona:
Romero Hortelano, Miguel

Foto de perfil
Dirección de correo electrónico
ORCID
0000-0001-7923-8297
Fecha de nacimiento
Proyectos de investigación
Unidades organizativas
Puesto de trabajo
Apellidos
Romero Hortelano
Nombre de pila
Miguel
Nombre

Filtros

20232
Restablecer filtros

Ajustes

search.filters.applied.f.accessLevel: info:eu-repo/semantics/openAccess × Fecha de inicio: 2020 ×

Resultados de la búsqueda

Mostrando 1 - 2 de 2
  • Miniatura
    Publicación
    An Internet of Living Things based device for a better understanding of the state of the honey bee population in the hive during the winter months
    (Elsevier, 2023-09) Aguirre Arribas, Fernando; Romero Hortelano, Miguel
    Monitoring beekeeping processes is a research area that is increasingly attracting interest, not only in order to maximize honey productivity but also to preserve the bee’s health and its environment. This paper presents a low-cost low-invasive system that uses IoT technologies as MQ Telemetry Transport, MQTT, and Node-RED, in an open hardware platform easily reproducible and royalty-free, to capture in real-time valuable information in form of a 3D-grid to show how the bees are located within the hive during the winter months using spatial thermal data without the need to open the hive up, thereby preventing manual manipulation by the beekeeper which puts the bees welfare in jeopardy. This system can reveal unexpected or little-known bee behaviors, facilitating a more comprehensive analysis of the health and strength of a bee colony to help beekeepers make the most appropriate decisions to ensure the productivity of their hive.
  • Miniatura
    Publicación
    Maternal Supplementation with N-Acetylcysteine Modulates the Microbiota-Gut-Brain Axis in Offspring of the Poly I:C Rat Model of Schizophrenia.
    (MDPI, 2023-04-20) Casquero Veiga, M.; Fernández, J.; Lamanna Rama, N.; Gómez Rangel, Vanessa; Gálvez Robleño, Carlos; Villar, C. J.; Lombó, F.; Abalo, R.; Desco, Manuel; Soto Montenegro, M. L.; Romero Hortelano, Miguel; Santa Marta Pastrana, Cristina María
    The microbiota-gut-brain axis is a complex interconnected system altered in schizophrenia. The antioxidant N-acetylcysteine (NAC) has been proposed as an adjunctive therapy to antipsychotics in clinical trials, but its role in the microbiota-gut-brain axis has not been sufficiently explored. We aimed to describe the effect of NAC administration during pregnancy on the gut-brain axis in the offspring from the maternal immune stimulation (MIS) animal model of schizophrenia. Pregnant Wistar rats were treated with PolyI:C/Saline. Six groups of animals were studied according to the study factors: phenotype (Saline, MIS) and treatment (no NAC, NAC 7 days, NAC 21 days). Offspring were subjected to the novel object recognition test and were scanned using MRI. Caecum contents were used for metagenomics 16S rRNA sequencing. NAC treatment prevented hippocampal volume reduction and long-term memory deficits in MIS-offspring. In addition, MIS-animals showed lower bacterial richness, which was prevented by NAC. Moreover, NAC7/NAC21 treatments resulted in a reduction of proinflammatory taxons in MIS-animals and an increase in taxa known to produce anti-inflammatory metabolites. Early approaches, like this one, with anti-inflammatory/anti-oxidative compounds, especially in neurodevelopmental disorders with an inflammatory/oxidative basis, may be useful in modulating bacterial microbiota, hippocampal size, as well as hippocampal-based memory impairments.